The integration of alien DNA is required to become a part of chromosome. As the DNA itself cannot multiply and replicate but rather requires a specific sequence for initiating its replication called origin of replication. Therefore, the alien DNA needs to be joined with the host DNA with the help of enzymes and linked to Ori, so as to be part of chromosome and replicate normally to produce its copies.
Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally?
Answers
Jitendra
The integration of alien DNA is required to become a part of chromosome. As the DNA itself cannot multiply and replicate but rather requires a specific sequence for initiating its replication called origin of replication. Therefore, the alien DNA needs to be joined with the host DNA with the help of enzymes and linked to Ori, so as to be part of chromosome and replicate normally to produce its copies.