Exonucleases are the enzymes which cleaves base pairs of DNA at their terminal ends and act on single strand of DNA or gaps in double stranded DNA. While, endonucleases cleaves DNA at any point except the terminal ends and can make cut on one strand or on both strands of double stranded DNA, e.g. Eco Rl and Hind II.
How is an exonuclease functionally different from an endonuclease? Give an example of any two endonucleases other than Sal I.
Answers
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Exonucleases are the enzymes which cleaves base pairs of DNA at their terminal ends and act on single strand of DNA or gaps in double stranded DNA. While, endonucleases cleaves DNA at any point except the terminal ends and can make cut on one strand or on both strands of double stranded DNA, e.g. Eco Rl and Hind II.